The 6’2″ 200-lb University of Oklahoma graduate learned the knuckleball from Hoyt Wilhelm, and in 1965 the two teamed in the Chicago bullpen that set a record with 53 saves. That year Fisher led AL pitchers with 82 relief appearances and 15 relief wins, and saved 24, all career highs. He also pitched two shutout innings in the All-Star Game. Fisher again led the AL with 67 appearances in 1966, but he split the season between Chicago and Baltimore. Fisher had come to the White Sox in a 1961 trade that sent Billy Pierce and Don Larsen to San Francisco.
Fisher was known for his great Donald Duck impersonation.