A catcher, Meyer broke in with Knoxville in the Southeastern League in 1910 and was up briefly with the White Sox and A’s in 1916-17. He played eight years at Louisville (American Association). In 1926 he succeeded Joe McCarthy as Louisville manager and won a pennant in his first year. He managed 16 years in the Yankees organization, won pennants in the International League, New York-Penn League, Eastern League, and American Association, and was named minor league manager of the year in 1939 at Kansas City. He was offered the Yankees job in 1946, but he had suffered a heart attack and did not think he was up to it. He returned to Kansas City and won another pennant. He went to the Pirates in 1948 and was named TSN Manager of the Year for a fourth-place finish. He later scouted for the Pirates.