A Chippewa Indian, Guyon was Jim Thorpe‘s football teammate at Carlisle and later an All-America at Georgia Tech (named as a tackle even though he was a triple-threat halfback). He played professional football from 1919 through 1926, often in the same backfield with Thorpe. He was named to both the National College Football Hall of Fame and the Pro Football Hall of Fame. But he preferred baseball and hit .329 over twelve summers, mostly with Atlanta (Southern Association) and Louisville (American Association) in the high minors. He stole 203 bases for his career, with a high of 45 in 1921 for Atlanta. Four times he scored over 100 runs, including 152 in 1925, his best year overall. He hit .363 that year, with 38 doubles, 17 triples, and 106 RBI, all full-season career highs. His football career and his hopes of making the ML in baseball were both ended by a knee injury sustained when he ran into an outfield fence in May 1928.