Trujillo made it to the majors as a middle reliever and spot starter for Boston in 1985. Late in 1986, Trujillo went to Seattle in a waiver deal connected to the trade that sent Dave Henderson and Spike Owen to the Red Sox for Rey Quinones. On September 20, 1986, in his second start as a Mariner, Trujillo threw a one-hitter (the second in franchise history) against the Royals. Trujillo started the 1987 season in the Mariners’ rotation but was bounced to the bullpen and then to Calgary (Pacific Coast League). Recalled in 1987, he was plagued by home runs, allowing 12 in 66 innings.